Starting GLP-1 therapy is an exciting step toward better health, but many people are surprised by how quickly treatment can affect hydration and electrolyte levels. Join us for practical, clinician-backed guidance to help maintain balance during treatment. How GLP-1 Therapy Affects Hydration GLP-1 receptor agonists — medications like semaglutide and tirzepatide — work by reducing appetite and slowing digestion. As a result, most people eat and drink noticeably less than befor